epitope corresponding to amino acids 847-1054 mapping near the C-terminus of AIDA-1 of human origin
Modification Notes
The b-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer’s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of AIDA-1 of mouse, rat and human origin by WB, IP, IF and ELISA recommended for detection of all AIDA-1 isoforms also reactive with additional species, including equine, canine, bovine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 847-1054 mapping near the C-terminus of AIDA-1 of human origin
Tissue Specificity
epitope corresponding to amino acids 847-1054 mapping near the C-terminus of AIDA-1 of human origin
recommended for detection of AIDA-1 of mouse, rat and human origin by WB, IP, IF and ELISA recommended for detection of all AIDA-1 isoforms also reactive with additional species, including equine, canine, bovine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.