| Product Name | NSUN1 Antibody (H-149) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 241-389 mapping within an internal region of NSUN1 of human origin |
| Modification Notes | The nucleolus consists of a number of specific proteins that play a critical role in the assembly of ribosomes, as well as in the maintenance and structural integrity of the nucleolus. NSUN1 (NOL1/NOP2/Sun domain family, member 1), also known as NOL1, p120, NOP120, NOP2 or Nucleolar protein 1, is an 812 amino acid nucleolar protein belonging to the methyltransferase superfamily. It is expressed in the G1 phase of the cell cycle and peaks during the early S phase. Considered a ribosomal RNA methyltransferase, NSUN1 may be involved in regulating the cell cycle and in increasing nucleolar activity that is associated with cell proliferation. NSUN1 is a possible marker for proliferation in neoplastic cells and in several cancer cells. Two isoforms exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NSUN1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 241-389 mapping within an internal region of NSUN1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 241-389 mapping within an internal region of NSUN1 of human origin |
| Entrez Gene | 4839 |
|---|
| Application Notes | recommended for detection of NSUN1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
