| Product Name | Zimp10 Antibody (H-95) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 881-975 mapping near the C-terminus of Zimp10 of human origin |
| Modification Notes | Zimp10, also known as ZMIZ1 (zinc finger, MIZ-type containing 1), MIZ or RAI17, is a 1,067 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one SP-RING-type zinc finger. Expressed in ovary, prostate, testis and spleen, Zimp10 interacts with AR (androgen receptor) and functions to increase the ligand-dependent transcriptional activity of AR and promote the sumoylation of AR, an event which is necessary for AR stimulation and overall activity. Multiple isoforms of Zimp10 exist due to alternative splicing events. The gene encoding Zimp10 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Zimp10 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 881-975 mapping near the C-terminus of Zimp10 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 881-975 mapping near the C-terminus of Zimp10 of human origin |
| Entrez Gene | 57178 |
|---|
| Application Notes | recommended for detection of Zimp10 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
