Application
Western blot analysis of LRRC18 expression in non-transfected: (A) and human LRRC18 transfected: (B) 293T whole cell lysates and mouse testis tissue extract (C).| Product Name | LRRC18 Antibody (FL-261) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-261 representing full length LRRC18 of human origin |
| Modification Notes | The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. LRRC18 (leucine-rich repeat-containing protein 18), also known as UNQ933, MGC34773 or VKGE9338, is a 261 amino acid protein that contains seven LRR repeats. Localized to the cytoplasm, LRRC18 may be involved in spermatogenesis and sperm maturation. LRRC18 is expressed as two isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 10. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LRRC18 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-261 representing full length LRRC18 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-261 representing full length LRRC18 of human origin |
| Entrez Gene | 474354 |
|---|
Application
Western blot analysis of LRRC18 expression in non-transfected: (A) and human LRRC18 transfected: (B) 293T whole cell lysates and mouse testis tissue extract (C).| Application Notes | recommended for detection of LRRC18 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
