epitope corresponding to amino acids 1-125 mapping at the N-terminus of PRDM8 of human origin
Modification Notes
Usually, two products are produced from a PR-domain family member; these products differ by the presence or absence of the PR domain. The PR-plus product is underexpressed or disrupted, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be an determining cause of malignancy. PRDM8 in particular is thought to be involved in transcriptional regulation. Its subcellular location is the nucleus and research indicates that PRDM8 contains three C2H2-type zinc fingers and one SET domain.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of PRDM8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-125 mapping at the N-terminus of PRDM8 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-125 mapping at the N-terminus of PRDM8 of human origin
recommended for detection of PRDM8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.