| Product Name | RGS13 Antibody (H-135) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-135 mapping at the N-terminus of RGS13 of human origin |
| Modification Notes | The regulators of G protein signaling (RGS) proteins inhibit heterotrimeric G protein signaling. RGS proteins work by functioning as GTPase-activating proteins (which increase the GTPase activity of G protein a subunits) thereby driving G proteins into their inactive GDP-bound form. RGS13 (regulator of G protein signaling 13) localizes in membrane and nuclear fractions, and is expressed predominantly in tonsil, thymus, lymph node, lung and spleen tissues. Within the lymphoid compartment, highest levels of RGS13 have been found in resting CD19-positive (B cells). Unlike most RGS proteins, RGS13 has no recognizable domain other than the RGS box, but because of its pre-valence in the immune system and lung and its ability to inhibit Gaq, Gai and cAMP generation, the function of RGS13 might be to modulate specific G protein-dependent signal transduction pathways in these regions. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RGS13 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-135 mapping at the N-terminus of RGS13 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-135 mapping at the N-terminus of RGS13 of human origin |
| Entrez Gene | 6003 |
|---|
| Application Notes | recommended for detection of RGS13 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
