| Product Name | NALP5 Antibody (M-250) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 201-450 mapping within an internal region of NALP5 of mouse origin |
| Modification Notes | NACHT-, LRR- and PYD-containing protein (NALP) family function in the regulation of apoptosis and inflammatory signaling pathways. Members of the NALP family (also designated Pyrin-containing APAF1-like proteins) include NALP1 through NALP11. Several family members, such as NALP1, NALP2, NALP3 and NALP6 influence NFkB and caspase pathways as components of the inflammasome. NALP5 (also designated MATER) is a maternal effect protein required for early embryonic development. Most short NALPs, such as NALP5, have a C-terminal leucine-rich repeat (LRR) region, an N-terminal pyrin (MEFV) domain (PYD), followed by a NACHT domain, and a NACHT-associated domain (NAD). The predicted 1,200-amino acid human NALP5 protein shares 53% sequence identity with the mouse protein. The gene which encodes the human NALP5 protein maps to chromosome 19q13.4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NALP5 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 201-450 mapping within an internal region of NALP5 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 201-450 mapping within an internal region of NALP5 of mouse origin |
| Entrez Gene | 23968 |
|---|
| Application Notes | recommended for detection of NALP5 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
