Application
Western blot analysis of RAP1GDS1 expression in rat brain (A) and human brain (B) tissue extracts.| Product Name | RAP1GDS1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 308-607 mapping at the C-terminus of RAP1GDS1 of human origin |
| Modification Notes | RAP1GDS1 (RAP1, GTP-GDP dissociation stimulator 1), also known as SmgGDS or GDS1, is a 607 amino acid protein that contains five ARM repeats and functions to stimulate the GDP/GTP exchange reaction of select small GTP-binding proteins. Additionally, RAP1GDS1 is thought to promote aberrant cell growth, playing a role in the development and metastasis of non-small cell lung carcinoma. Multiple isoforms of RAP1GDS1 exist due to alternative splicing events. The gene encoding RAP1GDS1 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RAP1GDS1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 308-607 mapping at the C-terminus of RAP1GDS1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 308-607 mapping at the C-terminus of RAP1GDS1 of human origin |
| Entrez Gene | 5910 |
|---|
Application
Western blot analysis of RAP1GDS1 expression in rat brain (A) and human brain (B) tissue extracts.| Application Notes | recommended for detection of RAP1GDS1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
