Application
Western blot analysis of APPBP2 expression in mouse hypothalamus (A) and mouse cerebellum (B) tissue extracts.| Product Name | APPBP2 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminal of APPBP2 of human origin |
| Modification Notes | APPBP2 (∫-Amyloid precursor protein-binding protein2), also known as protein interacting with APP tail 1 (PAT1) or Ara67, is a hydrophilic, microtubule binding protein that functions in the trafficking of ∫-Amyloid precursor protein. It is expressed in a variety of cell types and localizes to the cytoplasm. APPBP2 shares homology with kinesin light chain. It consists of a coiled-coil domain, PKC phosphorylation sites, four imperfect C-terminal tandem repeats, eight tetratricopeptide repeats and N- and C-terminal globular structures. APPBP2 recognizes and binds to the basolateral sorting sequence (BaSS) present in the cytoplasmic domain of the ∫-Amyloid precursor protein. In addition, APPBP2 interacts with the androgen receptor and suppresses androgen signaling. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of APPBP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminal of APPBP2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminal of APPBP2 of human origin |
| Entrez Gene | 10513 |
|---|
Application
Western blot analysis of APPBP2 expression in mouse hypothalamus (A) and mouse cerebellum (B) tissue extracts.| Application Notes | recommended for detection of APPBP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
