Western blot analysis of SPSY expression in non-transfected 293T: (A), mouse SPSY transfected 293T: (B), HeLa (C), K-562 (D) and Jurkat (E) whole cell lysates.
epitope corresponding to amino acids 202-331 mapping near the C-terminus of SPSY of human origin
Modification Notes
Spermine synthase (SPSY) catalyzes the production of spermine from spermidine (2). Spermine, a polyamine ubiquitously present in most organisms, is essential for normal cell growth and differentiation (3,5). Because absence of spermine increases sensitivity of cells to anti-tumor agents (4), spermine synthase (and other polyamine biosynthesis) is an attractive target for anti-neoplastic therapy (1).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Spermine synthase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 202-331 mapping near the C-terminus of SPSY of human origin
Tissue Specificity
epitope corresponding to amino acids 202-331 mapping near the C-terminus of SPSY of human origin
Western blot analysis of SPSY expression in non-transfected 293T: (A), mouse SPSY transfected 293T: (B), HeLa (C), K-562 (D) and Jurkat (E) whole cell lysates.
Application Notes
recommended for detection of Spermine synthase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.