Application
Western blot analysis of LCAT expression in non-transfected (A) and human LCAT transfected (B) whole cell lysates.| Product Name | LCAT Antibody (H-141) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 283-423 mapping near the C-terminus of LCAT of human origin |
| Modification Notes | The lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Members of the AB hydrolase subfamily include hepatic lipase (HL), endothelial lipase (EL), lipoprotein lipase (LPL), pancreatic lipase (PL), gastric lipase (GL) and the lecithin-cholesterol acyltransferase (LCAT). These family members play a crucial role in the metabolism of lipids. LCAT esterifies cholesterol, which is required for cholesterol transport. LCAT deficiency has been implicated in fish-eye disease, a rare genetic disorder of high density lipoprotein (HDL) metabolism. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of precursor and mature LCAT of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 283-423 mapping near the C-terminus of LCAT of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 283-423 mapping near the C-terminus of LCAT of human origin |
| Entrez Gene | 3931 |
|---|
Application
Western blot analysis of LCAT expression in non-transfected (A) and human LCAT transfected (B) whole cell lysates.| Application Notes | recommended for detection of precursor and mature LCAT of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
