epitope corresponding to amino acids 123-175 mapping within an internal region of TMED1 of human origin
Modification Notes
TMED1 (transmembrane emp24 protein transport domain containing 1), also known as ST2L, Il1rl1l or IL1RL1LG, is a 227 amino acid member of the EMP24/GP25L family. Widely expressed, TMED1 is a single-pass type I membrane protein containing one GOLD domain. Associated with membrane proteins, the GOLD (golgi dynamics) domain is a region of about 90 to 150 amino acids that mediates protein-protein interactions. The GOLD domain interacts with lipid, sterol or fatty acid-domains as well as with the RUN domain, which interacts with cytoskeletal filaments, of membrane proteins. Suggested to play a role in protein trafficking, TMED1 is encoded by a gene located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TMED1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 123-175 mapping within an internal region of TMED1 of human origin
Tissue Specificity
epitope corresponding to amino acids 123-175 mapping within an internal region of TMED1 of human origin
Western blot analysis of TMED1 expression in human stomach (A) and mouse liver (B) tissue extracts.
Application Notes
recommended for detection of TMED1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.