| Product Name | KCNC3 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of KCNC3 of human origin |
| Modification Notes | KCNC3 (Potassium voltage-gated channel subfamily C member 3) is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. The corneal epithelium is an important cell layer that functions to separate the corneal stroma from the anterior chamber of the eye. Increased expression of KCNC3 in confluent corneal endothelial cells suggests that the ionic current maintained by KCNC3 acts to regulate the hydration and transparency of the corneal stroma. Potassium channel regulation is also important for the high-frequency firing of cerebellar neurons. Defects, primarily missense mutations, in the gene encoding the KCNC3 protein have been attributed to neurological developmental disorders and adult onset neurological diseases. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of KCNC3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with KCNC4 also reactive with additional species, including porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of KCNC3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of KCNC3 of human origin |
| Entrez Gene | 3748 |
|---|
| Application Notes | recommended for detection of KCNC3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with KCNC4 also reactive with additional species, including porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
