| Product Name | Ribosomal Protein L6 Antibody (H-131) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 41-171 mapping within an internal region of Ribosomal Protein L6 of human origin |
| Modification Notes | Mammalian ribosomal proteins are encoded by multigene families that consist of processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L6, also known as RPL6, TAXREB107 or TXREB1, is a 288 amino acid component of the large ribosomal 60S subunit. Localized to the cytoplasm, Ribosomal Protein L6 binds specifically to domain C of the tax-responsive element (FOXN2) of human T-cell leukemia virus type 1, thereby regulating tax-mediated transcriptional activation. Ribosomal Protein L6 is upregulated in multi-drug resistant (MDR) gastric cancer cells and is implicated in Noonan syndrome, a congenital genetic condition characterized by impaired blood clotting, short stature and indentation of the chest. Two isoforms exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Ribosomal Protein L6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 41-171 mapping within an internal region of Ribosomal Protein L6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 41-171 mapping within an internal region of Ribosomal Protein L6 of human origin |
| Entrez Gene | 6128 |
|---|
| Application Notes | recommended for detection of Ribosomal Protein L6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
