Application
Western blot analysis of PSPH expression in non-transfected 293T: (A), mouse PSPH transfected 293T: (B) and SK-N-SH (C) whole cell lysates.Application
Western blot analysis of PSPH expression in non-transfected 293T: (A), human PSPH transfected 293T: (B) and SK-N-SH (C) whole cell lysates.| Product Name | PSPH Antibody (FL-225) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-225 representing full length PSPH of human origin |
| Modification Notes | Serine is an amino acid required for protein and nucleotide synthesis that may also be involved in cell to cell signaling. PSPH, also known as phosphoserine phosphatase or PSP, is a 225 amino acid Mg(2+)-dependent enzyme that catalyzes the last and irreversible step in the biosynthesis of serine from carbohydrates, which is the hydrolysis of O-phosphoserine. In the embryonic brain, PSPH is highly expressed in periventricular neural progenitors where it may have a role in neural stem cell proliferation. A lack of PSPH in humans has been shown to cause pre- and postnatal growth retardation as well as moderate psychomotor retardation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PSPH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-225 representing full length PSPH of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-225 representing full length PSPH of human origin |
| Entrez Gene | 5723 |
|---|
Application
Western blot analysis of PSPH expression in non-transfected 293T: (A), mouse PSPH transfected 293T: (B) and SK-N-SH (C) whole cell lysates.
Application
Western blot analysis of PSPH expression in non-transfected 293T: (A), human PSPH transfected 293T: (B) and SK-N-SH (C) whole cell lysates.| Application Notes | recommended for detection of PSPH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
