| Product Name | CYP4B1 Antibody (H-80) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 171-250 mapping within an internal region of CYP4B1 of human origin |
| Modification Notes | Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP4B1 (cytochrome P450, family 4, subfamily B, polypeptide 1), also known as CYPIVB1 or P-450HP, is a 511 amino acid peripheral membrane protein of the endoplasmic reticulum and microsome that belongs to the cytochrome P450 family. Expressed in lung and liver, CYP4B1 is involved in NADPH-dependent electron transport pathway and oxidizes xenobiotics, fatty acids and steroids. CYP4B1 is encoded by a gene that maps to human chromosome 1p33 and exists as two alternatively spliced isoforms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CYP4B1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 171-250 mapping within an internal region of CYP4B1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 171-250 mapping within an internal region of CYP4B1 of human origin |
| Entrez Gene | 1580 |
|---|
| Application Notes | recommended for detection of CYP4B1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
