Application
Western blot analysis of human recombinant TMEFF1 fusion protein.| Product Name | TMEFF1 Antibody (H-57) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 204-260 mapping within an internal region of TMEFF1 of human origin |
| Modification Notes | TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are members of the EGF-like protein family and are predominantly expressed in the brain. The structure of TMEFF1 is that of a transmembrane protein with a highly conserved cytoplasmic tail, two follistatin domains and one modified EGF domain in its extracellular region. TMEFF1 is expressed on the cell membrane, and may behave as a tumor suppressor gene in brain cancers. It inhibits nodal but not activin signaling by binding to Cripto, the nodal co-receptor, and is also involved in the regulation of BMPs. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMEFF1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 204-260 mapping within an internal region of TMEFF1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 204-260 mapping within an internal region of TMEFF1 of human origin |
Application
Western blot analysis of human recombinant TMEFF1 fusion protein.| Application Notes | recommended for detection of TMEFF1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
