Application
Western blot analysis of MAB21L expression in non-transfected: (A) and human MAB21L transfected: (B) 293T whole cell lysates.Application
Western blot analysis of MAB21L expression in non-transfected: (A) and human MAB21L transfected: (B) 293T whole cell lysates.Application
Western blot analysis of MAB21L expression in HeLa nuclear extract.| Product Name | MAB21L Antibody (K-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of MAB21L1 of human origin |
| Modification Notes | MAB21L (mab-21-like 1), also known as CAGR1, is a 359 amino acid nuclear protein expressed in cerebellum and skeletal muscle. A member of the mab21 family, MAB21L is required for several aspects of embryonic development including normal development of the eye and cerebellum. MAB21L is similar to the MAB-21 cell fate-determining gene found in Caenorhabditis elegans, and it is suggested that the expansion of a trinucleotide repeat region in the 5' UTR of MAB21L may play a role in a variety of psychiatric disorders. MAB21L is encoded by a gene located on human chromsome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is a deadly syndrome associated with chromosome 13. The few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MAB21L1 and MAB21L2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other MAB family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of MAB21L1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of MAB21L1 of human origin |
Application
Western blot analysis of MAB21L expression in non-transfected: (A) and human MAB21L transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of MAB21L expression in non-transfected: (A) and human MAB21L transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of MAB21L expression in HeLa nuclear extract.| Application Notes | recommended for detection of MAB21L1 and MAB21L2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other MAB family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
