| Product Name | GULP Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of GULP of human origin |
| Modification Notes | GULP (engulfment adaptor PTB domain containing 1) is a 304 amino acid protein encoded by the human gene GULP1. GULP is believed to function as an adapter protein, as it is required for efficient phagocytosis of apoptotic cells. GULP also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GULP are associated with increases in cellular levels of GTP-bound ARF6. Found as a homodimer, GULP, interacts with Clathrin, GDP-bound ARF6, but not with GTP-bound ARF6. It is also found as part of a complex composed of GULP1, CENTB1 and ARF6. GULP is widely expressed and can be detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GULP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of GULP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of GULP of human origin |
| Entrez Gene | 51454 |
|---|
| Application Notes | recommended for detection of GULP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
