| Product Name | TRF4 Antibody (H-172) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 371-542 mapping at the C-terminus of TRF4 of human origin |
| Modification Notes | DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. TRF4 (topoisomerase-related function protein 4-1), also known as POLS (polymerase sigma), POLK (polymerase ˚) or LAK-1, is a member of the Y-family of translesion DNA polymerases and is involved in DNA replication and repair. In addition, TRF4 may be involved in the cohesion of sister chromatids in association with the replicaton fork. Once replicated, sister chromatids must be held together until anaphase to ensure accurate chromosome segregation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TRF4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 371-542 mapping at the C-terminus of TRF4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 371-542 mapping at the C-terminus of TRF4 of human origin |
| Entrez Gene | 11044 |
|---|
| Application Notes | recommended for detection of TRF4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
