epitope corresponding to amino acids 377-461 mapping within an internal region of ELL2 of human origin
Modification Notes
ELL2 (RNA polymerase II elongation factor ELL2) is a 640 amino acid nuclear protein that belongs to the ELL/occludin family. This family is defined by a highly conserved domain of approximately 100 amino residues found within all eukaryotic occludin proteins and the RNA polymerase II elongation factor ELL. These elongation factors activate elongation by suppressing transient pausing by polymerase at many sites along the DNA and govern its interaction with RNA polymerase II and the ternary elongation complex. ELL2 may also contain a novel type of RNA polymerase II interaction domain that is capable of negatively regulating polymerase activity in promoter-specific transcription initiation in vitro.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ELL2 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with ELL1:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 377-461 mapping within an internal region of ELL2 of human origin
Tissue Specificity
epitope corresponding to amino acids 377-461 mapping within an internal region of ELL2 of human origin