Application
Western blot analysis of NHE-7 expression in Jurkat whole cell lysate.| Product Name | NHE-7 Antibody (K-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against NHE-7 of human origin |
| Modification Notes | Na+/H+ exchangers-1–8 (also designated NHE-1–8 or Na+/H+ antiporters) are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. Also, all NHE family members, except NHE-6 and NHE-7, which are located intracellularly, reside in the sarcolemmal membrane. NHE-7 interacts with tyrosinase related protein-1 (TRP-1) to regulate melanosome pH and tyrosinase activity in human melanoytes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of NHE-7 of mouse, rat, human, canine and zebra fish origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against NHE-7 of human origin |
|---|---|
| Tissue Specificity | raised against NHE-7 of human origin |
| Entrez Gene | 84679 |
|---|
Application
Western blot analysis of NHE-7 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of NHE-7 of mouse, rat, human, canine and zebra fish origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
