DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX31 (DEAD-box protein 31), also known as Helicain, is an 851 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. Localized to the nucleus, DDX31 is thought to function as an ATP-dependent RNA helicase that is involved in pre-mRNA splicing events, possibly playing a role in cell cycle progression. Four isoforms of DDX31 exist due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of DDX31 of human origin by WB, IP and ELISA: