Application
Western blot analysis of SCML2 expression in non-transfected 293T: (A), human SCML2 transfected 293T: (B) and KNRK (C) whole cell lysates.| Product Name | SCML2 Antibody (H-93) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. SCM (sex comb on midleg) is an important Drosophila PcG protein involved in transcriptional repression. SCML2 (sex comb on midleg-like 2) is a human homolog of this Drosophila protein. SCML2 is a ubiquitously expressed protein with predominant expression in placenta, testis and thymus. Upon DNA damage, SCML2 may be phosphorylated by ATR or ATM. Due to alternative splicing, two isoforms exist for this protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SCML2 of human origin by WB, IP, IF and ELISA non cross-reactive with other SCML family members | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 563-655 mapping near the C-terminus of SCML2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 563-655 mapping near the C-terminus of SCML2 of human origin |
| Entrez Gene | 10389 |
|---|
Application
Western blot analysis of SCML2 expression in non-transfected 293T: (A), human SCML2 transfected 293T: (B) and KNRK (C) whole cell lysates.| Application Notes | recommended for detection of SCML2 of human origin by WB, IP, IF and ELISA non cross-reactive with other SCML family members |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
