Application
Western blot analysis of LOK expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.| Product Name | LOK Antibody (F-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. LOK (Lymphocyte-oriented kinase), also known as STK10 (serine/threonine kinase 10), is a 968 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in lymphoid organs, LOK functions to catalyze the ATP-dependent phosphorylation of target proteins, such as MBP (myelin basic protein) and Histone H2A, thereby playing a role in signaling pathways throughout the cell. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of LOK of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of LOK of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 6793 |
|---|
Application
Western blot analysis of LOK expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
