epitope mapping within an internal region of ZBED4 of human origin
Modification Notes
The zinc finger BED domain-containing protein family (ZBED) is comprised of ZBED1, ZBED2, ZBED3, ZBED4 and ZBED5. They each contain one BED-type zinc finger domains with the exception of ZBED4, which contain 4 BED-type zinc finger domains. ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoded genes by binding specifically to 5'-TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. ZBED3 is an Axin-binding protein involved in Wnt/beta-catenin signaling modulation. ZBED4 expression has been shown in human and mouse retinas where it is thought to act as a regulatory protein in cone photoreceptors and Müller cells. The functions of ZBED2 and ZBED5 have yet to be elucidated.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ZBED4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with ZBED2 also reactive with additional species, including equine, canine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of ZBED4 of human origin
Tissue Specificity
epitope mapping within an internal region of ZBED4 of human origin
Western blot analysis of ZBED4 expression in HeLa whole cell lysate.
Application Notes
recommended for detection of ZBED4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with ZBED2 also reactive with additional species, including equine, canine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.