| Product Name | RP1L1 Antibody (N-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | RP1L1 (retinitis pigmentosa 1-like 1), also known as DCDC4B, is a 2480 amino acid retinal-specific protein that contains two doublecortin domains and a large repetitive C-terminal domain. Existing as multiple alternatively spliced isoforms, RP1L1 may play a role in the pathogenesis of retinitis pigmentosa, a group of genetic eye conditions that generally lead to night blindness and tunnel vision. The gene encoding RP1L1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RP1L1 of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of RP1L1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of RP1L1 of human origin |
| Entrez Gene | 94137 |
|---|
| Application Notes | recommended for detection of RP1L1 of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
