| Product Name | Tom1 Antibody (D-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Tom1 (Target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins. Human Tom1 shares 76% similarity with its chicken counterpart and 89% similarity with its mouse counterpart, suggesting a conserved function between species. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of Tom1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other Tom family members also reactive with additional species, including bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of Tom1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of Tom1 of human origin |
| Entrez Gene | 10043 |
|---|
| Application Notes | recommended for detection of Tom1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other Tom family members also reactive with additional species, including bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
