| Product Name | DENND1C Antibody (F-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | DENND1C (DENN/MADD domain containing 1 C), also known as FAM31C, is a 801 amino acid protein that contains a dDENN domain, DENN domain, and uDENN domain. DENND1C is thought to activate Rab13. The gene encoding DENND1C maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of DENND1C of m and h origin by WB, IF and ELISA non cross-reactive with DENND1A or DENND1B also reactive with additional species, including equine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of DENND1C of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of DENND1C of human origin |
| Entrez Gene | 79958 |
|---|
| Application Notes | recommended for detection of DENND1C of m and h origin by WB, IF and ELISA non cross-reactive with DENND1A or DENND1B also reactive with additional species, including equine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
