| Product Name | Spartin Antibody (H-141) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Spartin is a protein that may be involved in microtublue dynamics and endosomal trafficking. The Spartin protein contains a microtubule interacting and trafficking (MIT) molecule domain and is ubiquitously expressed, with highest levels observed in adipose tissue. A frameshift mutation in the Spartin gene (SPG20) causes spastic paraplegia 20, also designated Troyer syndrome, an autosomal recessive form of hereditary spastic paraplegia (HSP). HSP is an inherited neurological disorder characterized by lower extremity weakness and stiffness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Spartin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-141 mapping at the N-terminus of Spartin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-141 mapping at the N-terminus of Spartin of human origin |
| Entrez Gene | 23111 |
|---|
| Application Notes | recommended for detection of Spartin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
