Organic cations, such as quaternary ammoniums, are a group of compounds that carry a positive charge. OCTL1 (Organic cation transporter-like 3), also known as SLC22A13, OCTL3 or ORCTL3, belongs to the major facilitator superfamily which includes the organic cation transport family. OCTL1 is a conserved 551 amino acid transmembrane protein that has a fundamental role in mammalian systems. OCTL1 functions in the uptake of catecholamines and neurotoxic organic cations. Organic cation transport is essential for drug absorption, targeting and deposition. OCTL1 is highly expressed in glial cells and kidney tissue, and is ubiquitously expressed at low levels in all other tissues.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of OCTL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within a cytoplasmic domain of OCTL1 of human origin
Tissue Specificity
epitope mapping within a cytoplasmic domain of OCTL1 of human origin
Western blot analysis of OCTL1 expression in A-431 (A), KNRK (B), HL-60 (C), Hep G2 (D) and HeLa (E) whole cell lysates.
Application Notes
recommended for detection of OCTL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.