Application
Western blot analysis of ZNF70 expression in Jurkat whole cell lysate.| Product Name | ZNF70 Antibody (N-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF70 (Zinc finger protein 70), also known as Zinc finger protein N27C7-1, is a 446 amino acid nuclear protein that contains eleven C2H2-type zinc fingers. The gene encoding ZNF70 maps to chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNF70 of human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of ZNF70 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of ZNF70 of human origin |
| Entrez Gene | 7621 |
|---|
Application
Western blot analysis of ZNF70 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of ZNF70 of human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
