| Product Name | APOBEC3H Antibody (S-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | APOBEC3H (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H), also known as ARP10, is a 200 amino acid protein that belongs to the cytidine and deoxycytidylate deaminase family. Highly expressed in ovary, testis, colon, cerebellum, skin and fetal liver, APOBEC3H uses zinc as a cofactor to catalyze the deamination of cytidine to produce uridine, a reaction that edits mRNA and increases protein diversity. Additionally, via its catalytic activity, APOBEC3H can inhibit retroviral replication and it is thought to play a role in intrinsic immune system defense mechanisms. Overexpression of APOBEC3H may be associated with the formation of tumors, suggesting a role for APOBEC3H in carcinogenesis. Two isoforms of APOBEC3H exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of APOBEC3H of human origin by WB, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of APOBEC3H of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of APOBEC3H of human origin |
| Entrez Gene | 164668 |
|---|
| Application Notes | recommended for detection of APOBEC3H of human origin by WB, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
