Application
Western blot analysis of KRTAP10-8 expression in HEK293 (A), Hep G2 (B), HeLa (C), SW480 (D), A549 (E) and SK-N-MC (F) whole cell lysates.Application
Western blot analysis of KRTAP10-8 expression in HEK293 (A), Hep G2 (B), HeLa (C), SW480 (D), A549 (E) and SK-N-MC (F) whole cell lysates.| Product Name | KRTAP10-8 Antibody (N-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Hair is a structure that is unique to mammals. It plays an important role in the retention of heat, as well as sexual dimorphism, attraction of mates and protection of skin. The major components of hair are å-keratins and keratin-associated proteins (KRTAPs or KAPs), each of which are encoded by multigene families. Hair keratins form an intermediate filament (IF) network, which is embedded in an interfilamentous matrix consisting of KRTAPs. KRTAPS comprise three major groups, which are essential for the formation of rigid and resistant hair shafts through disulfide bond cross-linking or hydrophobic interactions with keratins. These groups are designated high cysteine (HS), which includes subfamilies 1, 2, 3, 10, 12, 16, 29 and 31, ultrahigh cysteine, including subfamilies 4, 5, 9, 17, 28, 30, 32 and 33, and high glycine-tyrosine (HGT), which includes subfamilies 6, 7, 8, 19, 20 and 21. In addition, subfamilies 11, 13, 24-27, 29, 34 and 35 have high serine content but relative low cysteine content. After further phylogenetic studies, subfamilies 14 and 15 have been grouped with subfamily 13 and subfamily 22 was combined with subfamily 19. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KRTAP10-8 of human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of KRTAP10-8 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of KRTAP10-8 of human origin |
| Entrez Gene | 386681 |
|---|
Application
Western blot analysis of KRTAP10-8 expression in HEK293 (A), Hep G2 (B), HeLa (C), SW480 (D), A549 (E) and SK-N-MC (F) whole cell lysates.
Application
Western blot analysis of KRTAP10-8 expression in HEK293 (A), Hep G2 (B), HeLa (C), SW480 (D), A549 (E) and SK-N-MC (F) whole cell lysates.| Application Notes | recommended for detection of KRTAP10-8 of human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
