Western blot analysis of FUZ expression in human lung tissue extract in the absence (A) and the presence (B) of immunizing peptide, mouse lung (C) tissue extract and rat lung (D) tissue extract.
FUZ is a 418 amino acid protein that localizes to both the cytoskeleton and the cytoplasm and is a human homolog of the Drosophila fuzzy protein. Existing as three alternatively spliced isoforms, FUZ is thought to be involved in regulating cytoskeletal function and may also play a role in maintaining cell polarity in epithelial cells. The gene encoding FUZ maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIP
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of a number of FUZ isoforms ranging from 269-418 amino acids in length of mouse rat and human origin by WB and IP
Tissue Specificity
recommended for detection of a number of FUZ isoforms ranging from 269-418 amino acids in length of mouse, rat and human origin by WB and IP
Western blot analysis of FUZ expression in human lung tissue extract in the absence (A) and the presence (B) of immunizing peptide, mouse lung (C) tissue extract and rat lung (D) tissue extract.
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.