| Product Name | NupL1 Antibody (T-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). NupL1 (Nucleoporin-like 1), also designated nucleoporin p58/p45, is a 599 amino acid protein that contains FG repeats and exists as a component of the p62 complex, which includes Nup62, Nup54, and NupL1. The p62 complex localizes near the central gated channel of the nuclear pore complex. Specifically, NupL1 interacts with SRP1-alpha and Importin p97 when they are together, but not with SRP1-alpha protein alone. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of NupL1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with isoforms p58 and 2 also reactive with additional species, including equine, canine, bovine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of NupL1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of NupL1 of human origin |
| Entrez Gene | 9818 |
|---|
| Application Notes | recommended for detection of NupL1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with isoforms p58 and 2 also reactive with additional species, including equine, canine, bovine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
