ABTB1 (ankyrin repeat and BTB/POZ domain-containing protein 1), also known as elongation factor 1A-binding protein or BPOZ, is a 478 amino acid protein localized to the cytoplasm. ABTB1 contains two ANK repeats and two BTB (POZ) domains. The BTB (POZ) domain is thought to be involved in protein-protein interactions, and may indicate a role of ABTB1 in developmental processes. It has also been suggested that ABTB1 may be a mediator of the PTEN growth-suppressive signaling pathway. ABTB1 is ubiquitously expressed in all fetal tissues, with lower levels of expression found in adult heart. ABTB1 exists as four isoforms produced by alternative splicing.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ABTB1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-300 mapping at the N-terminus of ABTB1 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-300 mapping at the N-terminus of ABTB1 of human origin
Western blot analysis of ABTB1 expression in mouse liver tissue extract.
Application Notes
recommended for detection of ABTB1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.