BAIAP3 (BAI1-associated protein 3), also known as BAP3, is a 1,187 amino acid transmembrane protein that contains two C2 domains, one MHD1 domain and one MHD2 domain. One of several members of the secretin receptor family, BAIAP3 is preferentially expressed in brain where it functions as an inhibitor of BAI-1 (brain-specific angiogenesis inhibitor I) and is thought to be involved in regulating synaptic functions. Additionally, BAIAP3 plays a role in the regulation of both tumor-associated exocytosis and oncogenic fusion and is a target of the tumor suppressor p53, suggesting that BAIAP3 is involved in cancer proliferation. Two isoforms of BAIAP3 exist due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of BAIAP3 of human origin by WB IP IF IHC(P) and ELISA
Tissue Specificity
recommended for detection of BAIAP3 of human origin by WB, IP, IF, IHC(P) and ELISA