Application
Western blot analysis of BMAL2 expression in JAR (A), NIH/3T3 (B), JEG-3 (C), EOC 20 (D) and KNRK (E) whole cell lysates.Application
Western blot analysis of BMAL2 expression in mouse placenta (A) and rat placenta (B) tissue extracts and JAR (C) and JEG-3 (D) whole cell lysates.Application
Western blot analysis of BMAL2 expression in MCF7 whole cell lysate.Application
Western blot analysis of BMAL2 expression in 293 whole cell lysate.| Product Name | BMAL2 Antibody (M-52) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | BMAL2, also known as ARNTL2 (aryl hydrocarbon receptor nuclear translocator-like 2), MOP9, CLIF or PASD9, is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BMAL2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 417-468 mapping near the C-terminus of BMAL2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 417-468 mapping near the C-terminus of BMAL2 of mouse origin |
Application
Western blot analysis of BMAL2 expression in JAR (A), NIH/3T3 (B), JEG-3 (C), EOC 20 (D) and KNRK (E) whole cell lysates.
Application
Western blot analysis of BMAL2 expression in mouse placenta (A) and rat placenta (B) tissue extracts and JAR (C) and JEG-3 (D) whole cell lysates.
Application
Western blot analysis of BMAL2 expression in MCF7 whole cell lysate.
Application
Western blot analysis of BMAL2 expression in 293 whole cell lysate.| Application Notes | recommended for detection of BMAL2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
