Application
Western blot analysis of RSRC2 expression in Jurkat whole cell lysate.| Product Name | RSRC2 Antibody (F-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Esophageal squamous cell carcinoma (ESCC) is cancer of the flat cells lining the esophagus, and is currently the ninth most frequent cancer in the world. While environmental risk factors, such as alcohol drinking and cigarette smoking, increase chances of ESCC, several genes are believed to be involved in the origin and/or progression of ESCC. The proteins encoded by these genes include p53, DCC, DEC1, DLEC1, RSRC2, p16 and TGF∫ RII. RSRC2 (arginine/serine-rich coiled-coil protein 2) is a 434 amino acid protein that is believed to function as a transcription factor involved in cell proliferation. Expressed ubiquitously and localized to the nucleus, RSRC2 may serve as a tumor suppressor of esophageal cancer. Overexpression of RSRC2 in an ESCC cell line inhibits cell proliferation, while the loss of RSRC2 is associated with tumor progression. This suggests that RSRC2 is a potential target for esophageal cancer therapy. RSRC2 is expressed as two isoforms produced by alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of RSRC2 of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against RSRC2 of human origin |
|---|---|
| Tissue Specificity | raised against RSRC2 of human origin |
| Entrez Gene | 65117 |
|---|
Application
Western blot analysis of RSRC2 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of RSRC2 of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
