Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing mitochondria localization.Application
Immunofluorescence staining of methanol-fixed HeLa cells showing mitochondrial localization.Application
Western blot analysis of CTP expression in HeLa whole cell lysate.Application
Western blot analysis of CTP expression in Hep G2 whole cell lysate.Application
Western blot analysis of CTP expression in non-transfected: (A) and mouse CTP transfected: (B) 293T whole cell lysates.| Product Name | CTP Antibody (T-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | CTP (citrate transport protein), also known as Tricarboxylate transport protein, SLC25A1 or SLC20A3, is a 311 amino acid mitochondrial multi-pass membrane protein that primarily functions to transport citrate across the mitochondrial inner membrane. Since it provides a carbon source for sterol and fatty acid biosynthesis, CTP is important for the bioenergetics of hepatic cells. The gene encoding CTP resides within a chromosomal region that is frequently deleted in patients that suffer from DiGeorge syndrome, a disease characterized by susceptibility to infection due to a deficit of T cells, cardiac malformations and tetany or seizures. Playing a significant role in intermediate metabolism, it appears that CTP function may be altered in type I diabetes and some cancers. CTP is highly expressed in adult ovary, gut liver, and testis, as well as in fetal kidney, lung, brain and liver. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CTP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of CTP of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of CTP of human origin |
| Entrez Gene | 6576 |
|---|
Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing mitochondria localization.
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing mitochondrial localization.
Application
Western blot analysis of CTP expression in HeLa whole cell lysate.
Application
Western blot analysis of CTP expression in Hep G2 whole cell lysate.
Application
Western blot analysis of CTP expression in non-transfected: (A) and mouse CTP transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of CTP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
