MOSPD3 (Motile sperm domain-containing protein 3), also known as CDS3, is a 235 amino acid multi-pass membrane protein that contains one MSP (major sperm protein) domain. The MSP domain, a critical component of sperm motility, has a seven-stranded beta sandwich and an immuoglobulin-like fold. MSP domains polymerize into helical, non-polar fragments that form a cytoskeleton made from intermeshed filaments. The intermeshed structure then assembles into large macromolecular complexes that play an important role in sperm movement. MOSPD3 is thought to be involved in development of the right ventricle, suggesting that the MSP domain may participate in cardiac development, as well as spermiogenesis. Three isoforms of MOSPD3 are expressed due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
recommended for detection of MOSPD3 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA