Application
Western blot analysis of CACHD1 expression in human fetal brain tissue extract.| Product Name | CACHD1 Antibody (U-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | CACHD1 (cache domain containing 1), also known as VWCD1, is a 1,274 amino acid single-pass type I membrane protein belonging to the calcium channel subunit alpha-2/delta family. Containing two cache domains and a VWFA (von Willebrand factor A) domain, CACHD1 is suggested to be involved in the regulation of voltage-dependent calcium channels. Existing as two isoforms produced by alternative splicing, CACHD1 is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of CACHD1 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of CACHD1 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 57685 |
|---|
Application
Western blot analysis of CACHD1 expression in human fetal brain tissue extract.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
