p53 is a DNA-binding protein that is involved in a variety of processes, including tumor suppression and apoptosis, DNA replication and repair, and cell cycle regulation. Normal cells and tissues express a low level of p53 under most circumstances, but p53 expression is induced by DNA damage and cellular stress. Wig-1 (wild type p53-induced gene 1) is a zinc finger protein that contains a putative nuclear localization signal (NLS) and is induced by p53. Wig-1 expression is increased by whole body gamma irradiation in these tissues as well as in spleen and lung.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of Wig-1 of mouse rat and human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of Wig-1 of mouse, rat and human origin by WB, IP and ELISA