WD repeat containing protein 13 (WDR13) is a 485 amino acid protein that is widely expressed in various adult and fetal tissues. WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. The gene encoding WDR13, which maps to chromosome Xp11.23, contains 9 exons, 8 introns and 6 WD-repeats. The subcellular localization of the WDR13 protein in the nucleus suggests that it may have a regulatory function. Two isoforms of this protein exist as a result of alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of WDR13 of mouse, rat, human and canine origin by WB, IP and ELISA