Application
Western blot analysis of ANKRD12 expression in Hep G2 whole cell lysate.| Product Name | ANKRD12 Antibody (G-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | ANKRD12 (ankyrin repeat domain 12), also known as ANCO2 (ankyrin repeat-containing cofactor 2), is a 2,062 amino acid protein that localizes to the nucleus and contains three ANK repeats. Expressed as two alternatively spliced isoforms that are present at moderate levels in lung, brain, heart, kidney, liver and testis, ANKRD12 interacts with p160 coactivators and is thought to recruit HDACs (histone deacetylases) to p160 complexes, thereby inhibiting ligand-dependent transactivation. The gene encoding ANKRD12 localizes to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ANKRD12 of mouse and human origin by WB IP and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of ANKRD12 of mouse and human origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 23253 |
|---|
Application
Western blot analysis of ANKRD12 expression in Hep G2 whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
