Application
Western blot analysis of IFI-44L expression in Jurkat nuclear extract.Application
Western blot analysis of IFI-44L expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining.| Product Name | IFI-44L Antibody (G-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Interferon-induced protein 44-like (IFI-44L), also known as C1orf29, is a 452 amino acid cytoplasmic protein that shares some sequence similarities with IFI-44. IFI-44 is a cytoplasmic protein that aggregates to form microtubule structures. The genes that encode IFI-44L and IFI-44 are located on chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of IFI-44L of human origin by WB, IP, IF, IHC(P) and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against IFI-44L of human origin |
|---|---|
| Tissue Specificity | raised against IFI-44L of human origin |
| Entrez Gene | 10964 |
|---|
Application
Western blot analysis of IFI-44L expression in Jurkat nuclear extract.
Application
Western blot analysis of IFI-44L expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining.| Application Notes | recommended for detection of IFI-44L of human origin by WB, IP, IF, IHC(P) and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
