| Product Name | ANKRD12 Antibody (L-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | ANKRD12 (ankyrin repeat domain 12), also known as ANCO2 (ankyrin repeat-containing cofactor 2), is a 2,062 amino acid protein that localizes to the nucleus and contains three ANK repeats. Expressed as two alternatively spliced isoforms that are present at moderate levels in lung, brain, heart, kidney, liver and testis, ANKRD12 interacts with p160 coactivators and is thought to recruit HDACs (histone deacetylases) to p160 complexes, thereby inhibiting ligand-dependent transactivation. The gene encoding ANKRD12 localizes to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ANKRD12 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of ANKRD12 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of ANKRD12 of human origin |
| Entrez Gene | 23253 |
|---|
| Application Notes | recommended for detection of ANKRD12 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
