Application
Western blot analysis of sarcosine dehydrogenase expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Product Name | sarcosine dehydrogenase Antibody (Z-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Sarcosine dehydrogenase, also known as SARDH, SAR, SDH, SARD or DMGDHL1, is a 918 amino acid protein that localizes to the mitochondrial matrix and is involved in the amine and polyamine degradation pathway. Using FAD as a cofactor, sarcosine dehydrogenase catalyzes the oxidative demethylation of sarcosine, a reaction that results in the formation of formaldehyde and glycine from sacrosine. Defects in the gene encoding sarcosine dehydrogenase are associated with sarcosinemia, a relatively benign metabolic disorder characterized by excess sarcosine in plasma and urine. The gene encoding sarcosine dehydrogenase maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of sarcosine dehydrogenase of mouse rat human and zebrafish origin by WB IP IF IHC(P) and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of sarcosine dehydrogenase of mouse, rat, human and zebrafish origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 1757 |
|---|
Application
Western blot analysis of sarcosine dehydrogenase expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
