| Product Name | Semenogelin-1/2 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Semenogelin, secreted high molecular weight seminal vesicle (HMV-SC) proteins, are the predominant protein found in semen. Semenogelin-1 and Semenogelin-2 are digested by PSA (prostate-specific antigen) in semen which leads to liquefaction and release of motile spermatozoa. Semenogelin-1 is a natural substrate of PSA. The Semenogelin precursor is processed to produce alpha-inhibin 31 and alpha-inhibin 92 active peptides. Semenogelin is involved in the formation of the gel matrix that encases ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins contribute to sperm movement activation. Semenogelin can form a complex with Eppin, an epididymal protease inhibitor. This complex of eppin and semenogelin can provide antimicrobial activity for spermatozoa. It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract. The genes encoding the two semenogelin proteins are found in a cluster on chromosome 20. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Semenogelin-1 precursor, &alpha-inhibin 31, &alpha-inhibin 92 and Semenogelin-2 of human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Semenogelin-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Semenogelin-1 of human origin |
| Entrez Gene | 6406 |
|---|
| Application Notes | recommended for detection of Semenogelin-1 precursor, &alpha-inhibin 31, &alpha-inhibin 92 and Semenogelin-2 of human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
